Dual checkpoint inhibitor induced autoimmune encephalitis

نویسندگان
چکیده

منابع مشابه

PD-1 Checkpoint Inhibitor Associated Autoimmune Encephalitis

OBJECTIVE To report first-hand narrative experience of autoimmune encephalitis and to briefly review currently available evidence of autoimmune encephalitis in cancer patients treated with immune checkpoint inhibitors. SETTING A case study is presented on the management of a patient who developed autoimmune encephalitis during nivolumab monotherapy occurring after 28 weeks on anti-PD-1 monoth...

متن کامل

Autoimmune Encephalitis

autoimmune encephalitis (aiE) associated with neural autoantibodies is increasingly recognized as a cause of subacute onset amnesia, confusion, and seizures. in the past decade, several key antibody targets have been identified in aiE. These include the N-methyl d-aspartate (NMda) receptors, voltage-gated potassium channel complexes—in particular leucine-rich glioma inactivated 1 (lGi1) and glu...

متن کامل

Autoimmune Encephalitis.

The term autoimmune encephalitis is used to describe a group of disorders characterised by symptoms of limbic and extra-limbic dysfunction occurring in association with antibodies against synaptic antigens and proteins localised on the neuronal cell surface. In recent years there has been a rapidly expanding knowledge of these syndromes resulting in a shift in clinical paradigms and new insight...

متن کامل

O 19: Treatment and Porognosis of Autoimmune Encephalitis

AE is a serious medical condition in which the immune system attacks the brain, impairing function. With rapid diagnosis and appropriate treatment, many patients recover most or all functions. However, not all patients experience full recovery; with approximately 6% mortality and other patients who never regain significant brain and/or bodily functions. Autoimmune encephalitis can pro...

متن کامل

O18: Autoimmune Encephalitis (Pathophysiology, Clinical Signs and Diagnos Tic Tests)

Autoimmune encephalitis is a difficult clinical diagnosis due to the similarities in the clini­cal, imaging and laboratory findings of many forms of autoimmune and infectious encephalitis. Autoimmune encephalitis involves several types: The first group includes the classic paraneo­plastic disorders associated with antibodies to intracellular antigens. The second group involves autoanti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Arhiv za onkologiju

سال: 2019

ISSN: 0354-7310,1450-9520

DOI: 10.2298/aoo181230003e